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Cat. No.	Product Name	Target	Signaling Pathways
T6393	ARQ 621	Kinesin	Cytoskeletal Signaling
	ARQ 621 是一种变构和选择性 Eg5 有丝分裂运动蛋白抑制剂，具有抗肿瘤活性。
T36816	S-trityl-L-Cysteine STLC	Kinesin	Cytoskeletal Signaling
	S-Trityl-L-cysteine 是别构驱动蛋白Eg5的选择性抑制剂。rityl-L-cysteine 抑制基础 ATPase 活性的IC50为 1 μM，抑制微管激活的 ATPase 活性的IC50为 140 nM。S-Trityl-L-cysteine 显示出抗肿瘤活性。
T77586	Eg5-IN-1	Kinesin	Cytoskeletal Signaling
	Eg5-IN-1 是一种有效的驱动蛋白家族运动蛋白 (Eg5) 抑制剂，对 Eg5 的 IC50 值为 1.97 µM。Eg5-IN-1 可用于研究癌症。
T4048	Monastrol (±)-Monastrol	Apoptosis; Kinesin	Apoptosis; Cytoskeletal Signaling
	Monastrol ((±)-Monastrol) 是一种具有高效性和细胞渗透性的有丝分裂驱动蛋白Eg5的抑制剂，IC50值为 14 μM。
T3120	K858 (Racemic) K858 Racemic,K858	Apoptosis; Kinesin	Apoptosis; Cytoskeletal Signaling
	K858 Racemic (K858) 是一种选择性有丝分裂驱动蛋白 Eg5 抑制剂，以 ATP 非竞争性方式起作用，IC50值为 1.3 μM。
T9682	AZD-4877 AZD4877	Apoptosis; Kinesin	Apoptosis; Cytoskeletal Signaling
	AZD-4877 是一种高效的纺锤体驱动蛋白 (Eg5) 抑制剂，对其 IC50 值为 2 nM。 AZD-4877 是 Ispinesib 的另一种构型，能够抑制细胞有丝分裂，诱导形成单极纺锤体表型，介导细胞凋亡(Apoptosis)。 AZD-4877 具有抗肿瘤活性，对循环外周血单核细胞 (PBMC)有抑制作用。
T4649	(S)-Monastrol	Kinesin	Cytoskeletal Signaling
	(S)-Monastroll is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.
T24150	HR22C16 HR-22-C-16,HR 22 C 16
	HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.
T11859	Litronesib Racemate LY-2523355 Racemate,KF-89617 Racemate	Others	Others
	Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.
T25418	Filanesib TFA Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA
	Filanesib (ARRY-520) targets the kinesin spindle protein (KSP) with potential antineoplastic activity. ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during
T11859L	Litronesib KF-89617,LY-2523355	Kinesin	Cytoskeletal Signaling
	Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.
T30308	BDPSB
	BDPSB is a highly efficient photocontroller of mitotic kinesin Eg5 ATPase activity.
T68743	AZD4877 HCl
	AZD4877 is a synthetic kinesin spindle protein (KSP) inhibitor with potential antineoplastic activity. KSP inhibitor AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which may result in the inhibition of mitotic spindle assembly; activation of the spindle assembly checkpoint; induction of cell cycle arrest during the mitotic phase; and cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic processes, such as neur...
T78125	PVZB1194	Kinesin	Cytoskeletal Signaling
	PVZB1194是一种联苯型激酶Eg5（亦称KIF11）抑制剂，与细胞周期相关，可以通过抑制Eg5的ATP酶活性导致细胞周期阻滞和细胞凋亡，从而显现抗癌潜力。该化合物与α4/α6变抗袋结合，展现ATP竞争性活性。

化合物

Cat.No: T6393

Target: Kinesin

S-trityl-L-Cysteine

Cat.No: T36816

Synonym: STLC

Target: Kinesin

Cat.No: T77586

Target: Kinesin

Cat.No: T4048

Synonym: (±)-Monastrol

Target: Apoptosis, Kinesin

Cat.No: T3120

Synonym: K858 Racemic,K858

Target: Apoptosis, Kinesin

Cat.No: T9682

Synonym: AZD4877

Target: Apoptosis, Kinesin

Cat.No: T4649

Target: Kinesin

Cat.No: T24150

Synonym: HR-22-C-16,HR 22 C 16

Litronesib Racemate

Cat.No: T11859

Synonym: LY-2523355 Racemate,KF-89617 Racemate

Target: Others

Cat.No: T25418

Synonym: Filanesib trifluoroacetic acid,ARRY-520 TFA,ARRY 520 TFA,ARRY520 TFA

Cat.No: T11859L

Synonym: KF-89617,LY-2523355

Target: Kinesin

Cat.No: T30308

Cat.No: T68743

Cat.No: T78125

Target: Kinesin

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